OPBG is a Scientific Institute for Research, Hospitalization and Health Care and an Academic Medical Center. It is Italy’s main paediatric Hospital and provides third level health care for children while performing basic, clinical and translational research activities. OPBG is widely recognized as referral centre for all paediatrics specialties at national and international level. OPBG has a total permanent staff of aprox 2,500, of which 550 physicians, 45 biologists and pharmacists, involved both in clinical and in research activities. All pediatric specialties are present in the hospital that is accreditated by Joint Commision International. The hospital is particularly reputated for treatment of heart disease in neonates, infants and children being the largest pediatric heart unit in Italy.